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Modeling the 3D Conformation of Genomes

By: (Edited by) Guido Tiana , (Edited by) Luca Giorgetti

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Ksh 32,400.00

Format: Hardback or Cased Book

ISBN-10: 1138500798

ISBN-13: 9781138500792

Series: Series in Computational Biophysics

Publisher: Taylor & Francis Ltd

Imprint: CRC Press

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Jan 23rd, 2019

Print length: 370 Pages

Weight: 710 grams

Dimensions (height x width x thickness): 16.40 x 24.10 x 2.40 cms

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This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, and predicting 3D genome structure.

This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.


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