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Adipose Tissue and Inflammation (Oxidative Stress and Disease)

By: Atif B. Awad (Edited by) , Peter G. Bradford (Edited by)

Manufacture on Demand

Ksh 48,150.00

Format: Hardback or Cased Book

ISBN-10: 1420091301

ISBN-13: 9781420091304

Collection / Series: Oxidative Stress and Disease

Collection Type: Publisher collection

Publisher: Taylor & Francis Inc

Imprint: CRC Press Inc

Country of Manufacture: US

Country of Publication: GB

Publication Date: Oct 8th, 2009

Publication Status: Active

Product extent: 318 Pages

Weight: 570.00 grams

Dimensions (height x width x thickness): 24.50 x 16.60 x 2.20 cms

Product Classification / Subject(s): Cellular biology (cytology)

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Obesity leads to a host of pathologies, including cardiovascular disease, insulin resistance, and metabolic syndrome. This book focuses on the effects of obesity on systemic inflammation. It addresses the epidemiology of obesity-induced inflammation and the adipokine mediators that link adipose tissue to inflammation.

The American Obesity Association identifies obesity’s link to numerous medical conditions, including hypertension, type 2 diabetes, cardiovascular disease, several cancers, and a host of inflammatory disorders. Evidence indicates that inflammation has more than a corollary relation with obesity; that in fact, obesity itself manifests a low-grade, metabolically associated inflammation involving many of the same mediators associated with classic inflammation. Concurrent with our understanding, we have to recognize that more than a storage site for fat, adipose tissue itself is an essential endocrine organ that produces and secretes a host of hormones in response to varying physiologic and pathologic states.

Bringing together the research and findings of leading experts from across the world, Adipose Tissue and Inflammation focuses on the contribution of adipose tissue to local and systemic inflammation. Demonstrating the endocrine like nature of adipose tissue, this book—

  • Looks at the direct relation between adipokines and inflammation
  • Examines the role of adipose secreted hormones as mediators of inflammation
  • Details the inflammatory actions of adiponectin, leptin, and resistin
  • Discusses insulin and dietary fatty acids as modulators of inflammation

This book belongs to the groundbreaking CRC Press Series on Oxidative Stress and Disease. The series now includes more than two-dozen volumes that address the multiple ways that oxidative stress initiates and accelerates disease mechanisms. Most importantly, this book, like the series, offers invaluable information regarding nutritional and life style choices, and interventions that can be employed to prevent, control, and even ameliorate disease processes attributed to oxidative stress. While much of the information put forth on these pages is sobering, the authors also look at the anti-inflammatory properties of plant sterols and phytoestrogens and the role that antioxidants and polyphenols play in moderating adipose inflammation. Further research looks at the role of exercise and weight loss in reducing inflammation; and discusses pharmaceutical approaches to adipose tissue related-inflammation.


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